Cytomics emerging from cytometry
نویسندگان
چکیده
منابع مشابه
Hyperchromatic cytometry principles for cytomics using slide based cytometry.
BACKGROUND Polychromatic analysis of biological specimens has become increasingly important because of the emerging new fields of high-content and high-throughput single cell analysis for systems biology and cytomics. Combining different technologies and staining methods, multicolor analysis can be pushed forward to measure anything stainable in a cell. We term this approach hyperchromatic cyto...
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Recently, two major books have been published that summarize the historical aspects and recent achievements of practical flow cytometry (1,2). Both emphasize the role played by this newly developed technical discipline in the development of scientific (1) and diagnostic platforms during late 20th-century medicine (2). Indeed, the gray box called a flow cytometer is the result of a multidiscipli...
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SYSTEMS BIOLOGY Systems biology aims at the quantification of molecular elements and their interrelations in biological systems in response to perturbation to integrate the variety of information into mathematical network models and to correctly predict biological system response to stimuli (1–4). Although promising for single-cell systems such as bacteria, yeast, or cell cultures, difficulties...
متن کاملIntegrating cytomics and proteomics.
Systems biology along with what is now classified as cytomics provides an excellent opportunity for cytometry to become integrated into studies where identification of functional proteins in complex cellular mixtures is desired. The combination of cell sorting with rapid protein-profiling platforms offers an automated and rapid technique for greater clarity, accuracy, and efficiency in identifi...
متن کاملSpectral imaging perspective on cytomics.
BACKGROUND Cytomics involves the analysis of cellular morphology and molecular phenotypes, with reference to tissue architecture and to additional metadata. To this end, a variety of imaging and nonimaging technologies need to be integrated. Spectral imaging is proposed as a tool that can simplify and enrich the extraction of morphological and molecular information. Simple-to-use instrumentatio...
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ژورنال
عنوان ژورنال: Cell Proliferation
سال: 2006
ISSN: 0960-7722,1365-2184
DOI: 10.1111/j.1365-2184.2006.00392.x